Marc J. Ruitenberg

Feb 27, 2024 | nature.com | Marc J. Ruitenberg |Quan Nguyen

Spatial omics enables the molecular profiling of cells with the tissue context preserved. A new analytic approach shows how cellular neighborhood analysis and feature augmentation can spatially connect and cluster millions of cells into higher-order functional units.

Nov 24, 2023 | nature.com | Brad Balderson |Jun Xu |Laura F. Grice |Pui Yeng Lam |Priyakshi Kalita-de Croft |Sunil R. Lakhani | +2 more

AbstractSpatial transcriptomics (ST) technologies generate multiple data types from biological samples, namely gene expression, physical distance between data points, and/or tissue morphology. Here we developed three computational-statistical algorithms that integrate all three data types to advance understanding of cellular processes.