Marcella Rietschel

Aug 30, 2024 | nature.com | Danyang Li |Oliver Pain |Chiara Fabbri |Stephan Ripke |Annamaria Cattaneo |Mojca Z. Dernovsek | +12 more

Correction to: Translational Psychiatry https://doi.org/10.1038/s41398-024-02981-1, published online 19 July 2024In this article the author’s name Chiara Fabbri was incorrectly written as Fabbri Chiara. The original article has been corrected.

Jul 18, 2024 | nature.com | Danyang Li |Oliver Pain |Stephan Ripke |Annamaria Cattaneo |Joanna Hauser |Glyn Lewis | +12 more

AbstractCytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for antidepressant metabolism and polymorphisms of these genes have been determined to predict metabolite levels. Nonetheless, more evidence is needed to understand the impact of genetic variations on antidepressant response. In this study, individual clinical and genetic data from 13 studies of European and East Asian ancestry populations were collected.

Apr 24, 2024 | nature.com | Dominic B. Dwyer |Sergi Papiol |Fabian Streit |Marcella Rietschel |Bertram Müller-Myhsok |Peter Falkai | +4 more

AbstractThe response variability to repetitive transcranial magnetic stimulation (rTMS) challenges the effective use of this treatment option in patients with schizophrenia. This variability may be deciphered by leveraging predictive information in structural MRI, clinical, sociodemographic, and genetic data using artificial intelligence. We developed and cross-validated rTMS response prediction models in patients with schizophrenia drawn from the multisite RESIS trial.