Stephan Ripke

Aug 30, 2024 | nature.com | Danyang Li |Oliver Pain |Chiara Fabbri |Stephan Ripke |Annamaria Cattaneo |Mojca Z. Dernovsek | +12 more

Correction to: Translational Psychiatry https://doi.org/10.1038/s41398-024-02981-1, published online 19 July 2024In this article the author’s name Chiara Fabbri was incorrectly written as Fabbri Chiara. The original article has been corrected.

Jul 18, 2024 | nature.com | Danyang Li |Oliver Pain |Stephan Ripke |Annamaria Cattaneo |Joanna Hauser |Glyn Lewis | +12 more

AbstractCytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for antidepressant metabolism and polymorphisms of these genes have been determined to predict metabolite levels. Nonetheless, more evidence is needed to understand the impact of genetic variations on antidepressant response. In this study, individual clinical and genetic data from 13 studies of European and East Asian ancestry populations were collected.

Jan 4, 2024 | nature.com | Xiangrui Meng |Daniel F Levey |Dora Koller |Mark Adams |Miguel E. Rentería |Dan Stein | +42 more

AbstractMost genome-wide association studies (GWAS) of major depression (MD) have been conducted in samples of European ancestry. Here we report a multi-ancestry GWAS of MD, adding data from 21 cohorts with 88,316 MD cases and 902,757 controls to previously reported data. This analysis used a range of measures to define MD and included samples of African (36% of effective sample size), East Asian (26%) and South Asian (6%) ancestry and Hispanic/Latin American participants (32%).