Oliver Pain

Aug 30, 2024 | nature.com | Danyang Li |Oliver Pain |Chiara Fabbri |Stephan Ripke |Annamaria Cattaneo |Mojca Z. Dernovsek | +12 more

Correction to: Translational Psychiatry https://doi.org/10.1038/s41398-024-02981-1, published online 19 July 2024In this article the author’s name Chiara Fabbri was incorrectly written as Fabbri Chiara. The original article has been corrected.

Jul 18, 2024 | nature.com | Danyang Li |Oliver Pain |Stephan Ripke |Annamaria Cattaneo |Joanna Hauser |Glyn Lewis | +12 more

AbstractCytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for antidepressant metabolism and polymorphisms of these genes have been determined to predict metabolite levels. Nonetheless, more evidence is needed to understand the impact of genetic variations on antidepressant response. In this study, individual clinical and genetic data from 13 studies of European and East Asian ancestry populations were collected.

Jun 13, 2024 | medrxiv.org | Oliver Pain |Ammar Al-Chalabi |Cathryn M. Lewis

OP provides consultancy services for UCB pharma. AAC reports consultancies or advisory boards for Amylyx, Apellis, Biogen, Brainstorm, Cytokinetics, GenieUs, GSK, Lilly, Mitsubishi Tanabe Pharma, Novartis, OrionPharma, Quralis, and Wave Pharmaceuticals. CML sits on the Myriad Neuroscience Scientific Advisory Board and is a Key Opinion Leader for UCB Pharma. OP is supported by a Sir Henry Wellcome Postdoctoral Fellowship [222811/Z/21/Z].

Jun 3, 2024 | kcl.ac.uk | Oliver Pain |Cathryn M. Lewis

The new GenoPred pipeline enables researchers to easily calculate an individual’s likelihood of different health-related outcomes, such as disease and disorders or response to treatment, based on their genetics. Most health-related outcomes are underpinned by thousands of genetic variants. Inherited changes in each gene impacts our risk of different diseases.