Mari Mino-Kenudson

1 month ago | nature.com | Molly Thomas |Mari Mino-Kenudson |Kaia Miller |Alexandra-Chloé Villani

AbstractMicroscopic colitis (MC) is a chronic inflammatory disease of the large intestine and a common cause of chronic diarrhea in older adults. Here, we use single-cell RNA sequencing analysis of colonic mucosal tissue to build a cellular and molecular model for MC. Our results show that in MC, there is a substantial expansion of tissue CD8+ T cells, likely arising from local expansion following T cell receptor engagement.

Dec 12, 2023 | onlinelibrary.wiley.com | Mari Mino-Kenudson

Editorial Thoracic tumour pathology Mari Mino-Kenudson,  Corresponding Author Mari Mino-Kenudson Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Address for correspondence: M Mino-Kenudson, Department of Pathology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Warren 210, Boston, MA 02114, USA.