Marie-Christine Groleau

Oct 1, 2024 | biorxiv.org | Marie-Christine Groleau |Abderrahman Hachani |Matthew P. Padula |Timothy P. Stinear

AbstractPhenotypic diversity in bacteria often results from adaptation to changing environmental conditions and is exemplified by variable colony morphotypes. Discrete genomic changes and modulation in gene expression occur in Burkholderia pseudomallei undergoing adaptation. Alternatively, adapted colony morphotype variants of species belonging to the Burkholderia cepacia complex (Bcc) lose a complete replicon (the pC3 virulence megaplasmid), which affects their production of virulence factors.