Matthew P. Padula

Oct 1, 2024 | biorxiv.org | Marie-Christine Groleau |Abderrahman Hachani |Matthew P. Padula |Timothy P. Stinear

AbstractPhenotypic diversity in bacteria often results from adaptation to changing environmental conditions and is exemplified by variable colony morphotypes. Discrete genomic changes and modulation in gene expression occur in Burkholderia pseudomallei undergoing adaptation. Alternatively, adapted colony morphotype variants of species belonging to the Burkholderia cepacia complex (Bcc) lose a complete replicon (the pC3 virulence megaplasmid), which affects their production of virulence factors.

Jun 17, 2023 | analyticalsciencejournals.onlinelibrary.wiley.com | David Bishop |Matthew P. Padula |Blanksby SJ |David S Gertner

Canola analysis Five replicate canola extracts were prepared for each of the four cultivars according to the protocol outlined in section 2.2. Each sample was then analyzed with triplicate injections. Quality control samples were prepared by pooling together the five replicate extracts and analyzed on every 10th injection. Data processing was conducted using MS-DIAL [37] in metabolite mode to permit an in-house spectral library catered specifically for the identification of PIs [38].