Mark Daly Journalist Profile

Articles

Local clubs notable wins in FAI Junior Cup

Dec 6, 2024 | limerickpost.ie | Mark Daly

THERE were some notable weekend wins by local teams in the prized FAI Junior Cup. Fairview breezed into the last 32 with a 4-1 home defeat of Ballyheigue Athletic. Darragh Rainsford grabbed a brace of goals for the multiple competition winners, while there was one apiece for Shane Duggan and Cale Langton. There was advancement also for Janesboro courtesy of a 3-1 home victory. The crucial scores came from Aodh O’Hanluain, Kai Joyce and the ever-reliable Shane Clarke.
Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations - Nature Medicine

Aug 8, 2024 | nature.com | M. Austin Argentieri |Derrick Bennett |Ashwag Albukhari |Jun Lv |Iona Y. Millwood |Hannah Fry | +6 more

AbstractCirculating plasma proteins play key roles in human health and can potentially be used to measure biological age, allowing risk prediction for age-related diseases, multimorbidity and mortality. Here we developed a proteomic age clock in the UK Biobank (n = 45,441) using a proteomic platform comprising 2,897 plasma proteins and explored its utility to predict major disease morbidity and mortality in diverse populations.
Top Scottish KC Andrew Smith found guilty of professional misconduct

May 25, 2024 | bbc.com | Mark Daly

Top Scottish KC found guilty of professional misconductMark Daly,Investigations correspondentCompass ChambersA top Scottish KC has been found to have acted in a “serious and reprehensible” manner in a legal battle over a dating app business in which he had a “close personal involvement”. The Faculty of Advocates complaints committee found Andrew Smith KC failed to adhere to an advocate’s “fundamental obligations” and found him guilty of professional misconduct.
Post Office still pursued sisters after case thrown out

Feb 6, 2024 | news.yahoo.com | Mark Daly

Jacquie El Kasaby and Rose Stewart were not told the reason for the failed prosecutionThe Post Office continued to threaten two sisters over a £34,000 shortfall even after a criminal trial was ruled out over faulty computer evidence, the BBC has learned. A Glasgow prosecutor rejected the case in 2014 because of "issues" with the Horizon computer system. However, the Post Office did not tell Jacquie El Kasaby and Rose Stewart the reason for the failed prosecution.
Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes - Nature

Jan 15, 2024 | nature.com | Masahiro Kanai |Qingbo Wang |Jessica Alföldi |William Phu |Yossi Farjoun |Anne H. O’Donnell-Luria | +4 more

Correction to: Nature https://doi.org/10.1038/s41586-023-06045-0 Published online 6 December 2023In the version of this article initially published, data points did not appear in Supplementary Figs. 6–8, and are now included in the online version of the Supplementary Information. About this articleChen, S., Francioli, L.C., Goodrich, J.K. et al. Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes. Nature (2024).
Dozens more dancers allege ballet body-shaming

Dec 20, 2023 | msn.com | Mark Daly
More dancers allege body-shaming and bullying at UK ballet schools

Dec 19, 2023 | news.nestia.com | Mark Daly

Image source, BBC News Image caption, Clockwise from top left: Madeleine, Siân, Joe and Sapphire By Mark Daly BBC News Dozens more ballet dancers have described body-shaming and bullying at schools across the UK, following a BBC investigation earlier this year. One ex-Elmhurst Ballet School student says she was shut in a room by staff while having a mental health crisis. Another developed anorexia and came close to suicide after attending the London Vocational Ballet School.
More dancers allege body-shaming and bullying at UK ballet schools

Dec 19, 2023 | yahoo.com | Mark Daly

Dozens more ballet dancers have described body-shaming and bullying at schools across the UK, following a BBC investigation earlier this year. One ex-Elmhurst Ballet School student says she was shut in a room by staff while having a mental health crisis. Another developed anorexia and came close to suicide after attending the London Vocational Ballet School. Both schools said their records differ from the accounts given to the BBC and that student welfare was a priority.
A genomic mutational constraint map using variation in 76,156 human genomes - Nature

Dec 6, 2023 | nature.com | Masahiro Kanai |Qingbo Wang |Jessica Alföldi |Yossi Farjoun |Anne H. O’Donnell-Luria |Alicia Martin | +4 more

AbstractThe depletion of disruptive variation caused by purifying natural selection (constraint) has been widely used to investigate protein-coding genes underlying human disorders1,2,3,4, but attempts to assess constraint for non-protein-coding regions have proved more difficult.
Improving fine-mapping by modeling infinitesimal effects - Nature Genetics

Nov 30, 2023 | nature.com | Ran Ji Cui |Roy A Elzur |Masahiro Kanai |Jacob C. Ulirsch |Mark Daly |Benjamin M. Neale

AbstractFine-mapping aims to identify causal genetic variants for phenotypes. Bayesian fine-mapping algorithms (for example, SuSiE, FINEMAP, ABF and COJO-ABF) are widely used, but assessing posterior probability calibration remains challenging in real data, where model misspecification probably exists, and true causal variants are unknown. We introduce replication failure rate (RFR), a metric to assess fine-mapping consistency by downsampling.