Mark Sansom

Dec 18, 2023 | biorxiv.org | T. Bertie Ansell |Megan Healy |Claire Coupland |Mark Sansom

AbstractMembrane Bound O-acyltransferases (MBOATs) are membrane embedded enzymes which catalyse acyl chain transfer to a diverse group of substrates including lipids, small-molecules and proteins. Recent MBOAT structures reveal a conserved structural core, despite wide-ranging functional specificity across both prokaryotes and eukaryotes.