Martin Bahls

Feb 12, 2025 | nature.com | Johannes Hertel |Stefan Weiss |Malte Christoph Rühlemann |Corinna Bang |Andre Franke |Uwe Völker | +12 more

Sedentarism is characterized by low levels of physical activity, a risk factor for obesity and cardio-metabolic diseases. It can also adversely affect the composition and diversity of the gut microbiome which may result in harmful consequences for human health. While cardiorespiratory fitness (CRF) is inversely and independently associated with cardiovascular risk factors and diseases and all-cause mortality, the relationship between low CRF and the gut microbiome is not well known. A total of 3,616 individuals from two independent population-based cohorts of the Study of Health in Pomerania (SHIP-START and SHIP-TREND) performed standardized, symptom-limited cardiopulmonary exercise testing (CPET) and had faecal samples collected to determine gut microbiota profiles (16S rRNA gene sequencing). We analysed cross-sectional associations of CRF with the gut microbiome composition controlling for confounding factors. Lower CRF was associated with reduced microbial diversity, loss of beneficial short-chain fatty acid producing bacteria (i.e. Butyricoccus, Coprococcus, unclassified Ruminococcaceae or Lachnospiraceae) and an increase in opportunistic pathogens such as Escherichia/Shigella, or Citrobacter. Decreased cardiorespiratory performance was associated with a gut microbiota pattern that has been previously related to a proinflammatory state. These associations were independent of body weight or glycemic control.

Sep 28, 2023 | frontiersin.org | Universitat Pompeu Fabra |Sánchez González |Juan Luis |Martin Bahls

Introduction The rapid technological evolution experienced recently has meant significant progress, resulting in greater accessibility to knowledge generating changes in the needs of society (1). In the same way, these changes must also be implemented in higher education to promote active learning and thus improve the theoretical and practical results of future health professionals (2). Accordingly, lately, a new type of educational approach known as blended learning (BL) has emerged (1, 3).

Jul 25, 2023 | nature.com | Martin Bahls |Matthias Nauck

AbstractBackground and objectivesVarious cross-sectional studies have observed an association between high circulating concentrations of the adipokine chemerin and an unfavorable metabolic profile. However, the prognostic value of chemerin for the risk of associated diseases and mortality was examined only in a few studies mostly using small and highly selected patient populations.