Michael P. Menden

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Suppression of ferroptosis by vitamin A or radical-trapping antioxidants is essential for neuronal development - Nature Communications

Sep 1, 2024 | nature.com | Juliane Tschuck |Gabriele Ciceri |Jason Tchieu |Brent R. Stockwell |Lorenz Studer |Michael P. Menden | +1 more

AbstractThe development of functional neurons is a complex orchestration of multiple signaling pathways controlling cell proliferation and differentiation. Because the balance of antioxidants is important for neuronal survival and development, we hypothesized that ferroptosis must be suppressed to gain neurons.

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