-
Jan 23, 2025 | 
academic.oup.com | Shandong Agricultural |High-Efficiency Production |Michael Smith Laboratories
Proteins with Toll/interleukin-1 receptor (TIR) domains are widely distributed in both prokaryotes and eukaryotes, serving as essential components of immune signaling. Although monocots lack the major TIR-nucleotide-binding (NB)-leucine-rich repeat (LRR)-type (TNL) immune receptors, they possess a small number of TIR-only proteins, the function of which remains largely unknown.
-
Aug 29, 2024 | 
journals.plos.org | Alison McAfee |Michael Smith Laboratories |Niloofar Alavi-Shoushtari |Lan Anh Tran
Loading metrics Open Access Peer-reviewedResearch Article Citation: McAfee A, Alavi-Shoushtari N, Tran L, Labuschagne R, Cunningham M, Tsvetkov N, et al. (2024) Climatic predictors of prominent honey bee (Apis mellifera) disease agents: Varroa destructor, Melissococcus plutonius, and Vairimorpha spp. PLOS Clim 3(8): e0000485.
-
Jun 15, 2024 | 
academic.oup.com | Michael Smith Laboratories |Département de Biologie |Université Laval |Ville de Québec
Highbush blueberry [Vaccinium corymbosum L. (Ericales: Ericaceae)] is a major crop in Canada and the United States (Protzman 2021, Agriculture and Agri-Food Canada 2023) and fruit production is enhanced by insect pollination, which increases fruit weight by approximately 75% (Eeraerts et al. 2023).
-
Dec 28, 2023 | 
academic.oup.com | BC Canada |Michael Smith Laboratories |Columbia Canada |BC Cancer
Single cell segmentation is critical in the processing of spatial omics data to accurately perform cell type identification and analyze spatial expression patterns. Segmentation methods often rely on semi-supervised annotation or labeled training data which are highly dependent on user expertise. To ensure the quality of segmentation, current evaluation strategies quantify accuracy by assessing cellular masks or through iterative inspection by pathologists.
-
Dec 27, 2023 | 
onlinelibrary.wiley.com | Lei Tian |Michael Smith Laboratories |Josh Li |Yan Xu
INTRODUCTION Sclerotinia sclerotiorum (Lib.) de Bary is a notorious soilborne fungal pathogen with an extremely wide host range. This ascomycete can infect over 600 plant species, especially dicots (Boland & Hall, 1994; Liang & Rollins, 2018).
-
Nov 2, 2023 | 
academic.oup.com | Virginia Commonwealth |Michael Smith Laboratories |Xinyang Normal
With millions of protein sequences that have been collected (1), we are confronted with the great challenge of characterizing them functionally and structurally. These annotations are done at three levels: the atomic, amino acid (AA) and whole protein level. The notable atomic-level databases include Protein Data Bank (PDB) (2,3), the primary depository of experimentally solved structures, and AlphaFold DB (4), which houses putative structures predicted with AlphaFold2 (5).
-
Oct 2, 2023 | 
journals.plos.org | Julia Fine |Leonard Foster |Michael Smith Laboratories |Alison McAfee
Proteomics sample preparation. All queens that were alive at the conclusion of Round 1 (except for 1 PYR-1 queen lost during sampling) were shipped on dry ice to the University of British Columbia, where ovaries were dissected from previously frozen queens (n = 10 queens DIF-1, 10 MET-1, 9 PYR-1, 10 POS-CTRL, and 9 CTRL-1) under a dissecting scope and weighed.
-
Sep 1, 2023 | 02242-1/abstract&sz=64)
jbc.org | Byrne D.P |Michael Smith Laboratories |Jacob F Wardman |Peter Rahfeld
ABSTRACTSulfation is widespread in Nature, and plays an important role in modulating biological function. Among the strategies developed by microbes to access sulfated oligosaccharides as a nutrient source is the production of 6-sulfoGlcNAcases to selectively release 6-sulfoGlcNAc from target oligosaccharides. Thus far, all 6-sulfoGlcNAcases identified have belonged to the large GH20 family of β-hexosaminidases.
-
Jun 16, 2023 | 
academic.oup.com | Michael Smith Laboratories
When you visit web sites, they may store or retrieve data in your web browser. This storage is often necessary for basic functionality of the web site or the storage may be used for the purposes of marketing, analytics, and personalization of the web site such as storing your preferences.
-
Feb 27, 2023 | 
frontiersin.org | Michael Smith Laboratories
Yan Xu1, Yilan Qiu1, Yuelin Zhang1 and Xin Li2*
1University of British Columbia, Canada
2Michael Smith Laboratories, University of British Columbia, Canada
The final, formatted version of the article will be published soon.
Receive an email when it is updated
Sclerotinia sclerotiorum is a plant pathogenic fungus that causes white mold or stem rot diseases. It affects mostly dicotyledonous crops, resulting in significant economic losses worldwide.
