Mike Horton

Aug 28, 2024 | onlinelibrary.wiley.com | Metabolic Diseases |Mike Horton |Stephan Wenninger |Benedikt Schoser

INTRODUCTION Pompe disease (glycogen storage disease type II or acid maltase deficiency, Online Mendelian Inheritance in Man ID: 232300) is a rare inherited metabolic disorder in which deficiency of acid α-glucosidase leads to lysosomal glycogen accumulation [1]. Late onset or nonclassic Pompe disease can present at any age and is characterized by slowly progressive skeletal and respiratory muscle weakness, often leading to wheelchair and/or ventilator dependency [2, 3].

Jun 27, 2024 | bmjopenrespres.bmj.com | ADAM SMITH |Darren Greenwood |Mike Horton |Thomas B. Osborne

All analyses were performed using R Studio (R V.4.1.1). Descriptive summary statistics (mean, standard deviation (SD), count and percentage) were generated for the following patient demographic and clinical data: age, sex, ethnicity, smoking status, hospital admission, intensive care (ICU) admission. The scale characteristics for the three C19-YRSm subscales (SS, FD and OH) were derived including: mean (SD), median (inter-quartile range, IQR), score range and skewness (evaluated −0.5 to +0.5).

Aug 23, 2023 | medium.com | Mike Horton

MESSARI DePIN Sector Map Decentralized Physical Infrastructure Networks - DePIN is a rapidly growing class of public-use infrastructure necessary for next-generation AI, Wireless, and Robotics applications. GEODNET is the largest DePIN network addressing high-accuracy secure location services. Currently, there are 3000+ GEODNET satellite miners which form a large centimeter-accurate positioning network. GEODNET has published a peer-reviewed framework for its network in the Journal of Navigation.

Mar 2, 2023 | medium.com | Mike Horton

In a time of continued uncertainty and bad actors in the crypto space, GEODNET wants to make it clear we are committed to these values:GEODNET is committed to the long-term as a responsible Decentralized Physical Infrastructure Project (#DePIN) by building the biggest and highest quality Geo-Spatial Reference Network in the world. GEODNET is committed to maintaining transparency and integrity in all aspects of the project.