Mingkai Zhang

Aug 21, 2024 | nature.com | Mingkai Zhang |Matthew Chapman |Bhagyesh R. Sarode |James Chen |Eranthie Weerapana |Bingcong Xiong

AbstractAlthough aromatic rings are common elements in pharmaceutically active compounds, the presence of these motifs brings several liabilities with respect to the developability of a drug1. Nonoptimal potency, metabolic stability, solubility and lipophilicity in pharmaceutical compounds can be improved by replacing aromatic rings with non-aromatic isosteric motifs2.

Jan 31, 2024 | pubs.acs.org | Mingkai Zhang |Ling Zhu |Xingguo Wang

Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Agric. Food Chem. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).

Aug 10, 2023 | pubs.acs.org | Mingkai Zhang |Ling Zhu |Xingguo Wang

Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Agric. Food Chem. 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).

Jun 29, 2023 | onlinelibrary.wiley.com | Xiaohe Tan |Mingkai Zhang |Da Chen |Wenbin Li

Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.