Mingyao Li

Nov 4, 2024 | nature.com | Huasheng Yu |Saad S. Nagi |Dmitry Usoskin |Yizhou Hu |Otmane Bouchatta |Hanying Yan | +10 more

AbstractThe versatility of somatosensation arises from heterogeneous dorsal root ganglion (DRG) neurons. However, soma transcriptomes of individual human (h)DRG neurons—critical information to decipher their functions—are lacking due to technical difficulties. In this study, we isolated somata from individual hDRG neurons and conducted deep RNA sequencing (RNA-seq) to detect, on average, over 9,000 unique genes per neuron, and we identified 16 neuronal types.

Aug 8, 2024 | nature.com | Kyle Coleman |Mingyao Li

Spatial omics technologies have transformed biomedical research by offering detailed, spatially resolved molecular profiles that elucidate tissue structure and function at unprecedented levels. AI can potentially unlock the full power of spatial omics, facilitating the integration of complex datasets and discovery of novel biomedical insights.

May 25, 2023 | nature.com | Mingyao Li

Cite this articleLee, M.Y.Y., Li, M. Integration of multi-modal single-cell data. Nat Biotechnol (2023). https://doi.org/10.1038/s41587-023-01826-4Download citationPublished: 25 May 2023DOI: https://doi.org/10.1038/s41587-023-01826-4Share this articleAnyone you share the following link with will be able to read this content:Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative Subjects

Feb 3, 2023 | biorxiv.org | Klaus H. Kaestner |Mingyao Li

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