Mir-Farzin Mashreghi

Jan 3, 2024 | nature.com | Tobias Brunner |Frederik Heinrich |Gitta A. Heinz |Thomas Hofer |Mir-Farzin Mashreghi |Ralf Kühn | +5 more

AbstractThe pleiotropic alarmin interleukin-33 (IL-33) drives type 1, type 2 and regulatory T-cell responses via its receptor ST2. Subset-specific differences in ST2 expression intensity and dynamics suggest that transcriptional regulation is key in orchestrating the context-dependent activity of IL-33–ST2 signaling in T-cell immunity.