Miriam Huerta

Jul 2, 2024 | biorxiv.org | Miriam Huerta |Maria Luisa Guzman-Hernandez |Ana Elena Lopez-Romero |Rita Moran-Zendejas

AbstractThe Ca2+-dependent Cl- channel TMEM16A activity is vital for mammals. Critical functions such as blood pressure, pain, fluid and electrolyte secretion, peristalsis, and electrical activity depend on TMEM16A Cl- fluxes. Ciclosporin A (CsA) and FK506, two immunosuppressants that inhibit calcineurin (CaN), down-regulate TMEM16A function. However, the underlying mechanism remains undetermined.

Dec 29, 2023 | pnas.org | Isla Simpson |Vasileios Oikonomou |Miriam Huerta |Alexandra Sandéhn

Recent heat extremes, wildfires, and droughts have afflicted multiple regions including parts of South America, the Mediterranean, and Middle East as well as the southwestern United States. These events underscore the vulnerability of societies to ongoing climate change as well as the precarious dependence of societies and ecosystems upon fresh water, the terrestrial lifeblood.

Jul 26, 2023 | mdpi.com | Eduardo Garcia |Eduardo García |Marija Mojicevic |Miriam Huerta |Buket Alkan Tas

3. DiscussionFibronectin (Fn), a critical ECM protein whose functions are governed by its conformational activity, is receiving increasing attention due to its participation in various phases of tumor proliferation and other complications of medical importance such as Fn glomerulopathy [25,26,27]. In this study, the suitability of PEGAuTSNPs for use as platforms for IAs was successfully demonstrated.