Mohamed Ameen

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Articles

The benefits of developing talent through experiences

2 months ago | peoplemanagement.co.uk | Mohamed Ameen

Managers and employees are currently left to struggle with complex and difficult to apply competency-based development models. Typical competency-based development approaches do not support organisations to accelerate development or provide employees with a guide for managing their career growth. They mainly focus on centralising the development plans on the behaviours that describe the competency dimensions, not on the outcomes that define performance success within the organisation.
CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity

Nov 7, 2024 | cell.com | Chun Ching Liu |Mengcheng Shen |Yanxia Liu |Amit Manhas |Shane Zhao |Mao Zhang | +14 more

Keywordsdoxorubicincardio-oncologyCRISPR screeniPSCcarbonic anhydrasecardiomyoctyeglycolysisGet full text accessLog in, subscribe or purchase for full access. References1. Miller, K.D. ∙ Nogueira, L. ∙ Devasia, T. ... Cancer treatment and survivorship statistics, 2022CA Cancer J. Clin. 2022; 72:409-4362. Burridge, P.W. ∙ Li, Y.F. ∙ Matsa, E. ... Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicityNat. Med.
From Competency To Context: The Future Of Talent Leadership

Sep 24, 2024 | hr.com | Mohamed Ameen

Understanding the "why" behind leadership skills is crucial for aligning them with business objectives. A context-based approach to talent and leadership development improves precision in identifying and nurturing key leadership capabilities. Integrating business drivers into leadership development strategies enhances the relevance and effectiveness of talent programs. Every talent professional is aware that a well-defined talent & leadership strategy is important.
My Recommended 1:1 Format: Me, Us, and It

Aug 26, 2024 | medium.com | Mohamed Ameen

As someone who values regular check-ins with my team members and manager, I’ve found that a structured approach to our 1:1s helps me stay focused and ensure we’re making progress together. Over time, I’ve developed a format that consists of three parts: Me, Us, and It. Here’s how I like to break down each section:In this part, the conversation is all about me — my thoughts, feelings, goals, and experiences. This is where I share:• How I’m feeling: Honestly, what’s been on my mind lately?
Four key tips to help you develop a successful talent strategy

Nov 10, 2023 | peoplemanagement.co.uk | Mohamed Ameen

Many professionals believe that articulating an organisation’s talent strategy is similar to deploying a list of talent programmes, processes and practices. While these components enable a talent strategy, they are not a talent strategy by themselves. A talent strategy is a business strategy. It should be informed by (and inform) your organisational strategy. Organisations create a talent strategy by focusing most on critical talent outcomes deemed vital to executing the organisation’s strategy.
Biden will pay the price

Oct 29, 2023 | egyptindependent.com | Mohamed Ameen

It is certain that US President Biden will bear the brunt of the Gaza war alone, whether in terms of his political capital, history, or future. That is the least of it. The harsher consequences could be terrorist attacks in the US itself or on US embassies around the world. I recall here when former US President Barack Obama said that the situation in Gaza could lead to a hardening of the Palestinian position for generations to come. This is a fact.
Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency

Oct 21, 2023 | biorxiv.org | Surag Nair |Mohamed Ameen |Laksshman Sundaram |Anusri Pampari

AbstractEctopic expression of OCT4, SOX2, KLF4 and MYC (OSKM) transforms differentiated cells into induced pluripotent stem cells. To refine our mechanistic understanding of reprogramming, especially during the early stages, we profiled chromatin accessibility and gene expression at single-cell resolution across a densely sampled time course of human fibroblast reprogramming.
Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency

Oct 4, 2023 | biorxiv.org | Surag Nair |Mohamed Ameen |Laksshman Sundaram |Anusri Pampari

AbstractEctopic expression of OCT4, SOX2, KLF4 and MYC (OSKM) transforms differentiated cells into induced pluripotent stem cells. To refine our mechanistic understanding of reprogramming, especially during the early stages, we profiled chromatin accessibility and gene expression at single-cell resolution across a finely sampled time course of human fibroblast reprogramming.
Why people professionals must rethink talent management

Feb 17, 2023 | peoplemanagement.co.uk | Mohamed Ameen

In a labour market that’s tighter than ever, organisations seek opportunities to build, invest, and capitalise on talent economy. Much of the public dialogue in HR and talent management is on the next ground-breaking innovation – the promise of the ‘future of work’, analytics and artificial intelligence, amongst others. And yet, very little dialogue is on how organisations are missing the fundamentals and do not have a plan to close the gap.