Mulong Du

Featured in: Favicon

nature.com Favicon

frontiersin.org Favicon

springer.com Favicon

biomedcentral.com (+1) Favicon

science.org Favicon

aacrjournals.org (+1) Favicon

tmc.edu + 4 more

Articles

Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer - Nature Aging

2 weeks ago | nature.com | Yifei Cheng |Bin Xu |Mulong Du

AbstractThe clinical and pathological outcomes differ between early-onset (diagnosed in men ≤55 years of age) and late-onset prostate cancer, potentially attributed to the changes in hormone levels and immune activities associated with aging. Exploring the heterogeneity therein holds potential for developing age-specific precision interventions.
Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment - Nature Communications

Apr 7, 2024 | nature.com | Zhibin Hu |Mulong Du |Hongbing Shen

AbstractThe development of an effective survival prediction tool is key for reducing colorectal cancer mortality. Here, we apply a three-stage study to devise a polygenic prognostic score (PPS) for stratifying colorectal cancer overall survival.
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations - Nature Communications

Oct 2, 2023 | nature.com | Minta Thomas |Elisabeth Rosenthal |Lori C. Sakoda |Stephanie Schmit |Maria Timofeeva |Ceres Fernández-Rozadilla | +60 more

AbstractPolygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry data have sub-optimal performance in non-European ancestry populations, limiting their utility among these populations.
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations - Nature Communications

Oct 2, 2023 | nature.com | Minta Thomas |Elisabeth Rosenthal |Lori C. Sakoda |Stephanie Schmit |Maria Timofeeva |Ceres Fernández-Rozadilla | +60 more

AbstractPolygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry data have sub-optimal performance in non-European ancestry populations, limiting their utility among these populations.

Contact details

Emails

[email protected]

Socials & Sites

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.

Start Your 7-Day Free Trial →