Nao Tanaka

Jan 31, 2024 | nature.com | Yuki Ishikawa |Nao Tanaka |Mitsuteru Akahoshi |Takashi Matsushita |Akira Oka |Motohisa Yamamoto | +15 more

AbstractHere we report the largest Asian genome-wide association study (GWAS) for systemic sclerosis performed to date, based on data from Japanese subjects and comprising of 1428 cases and 112,599 controls. The lead SNP is in the FCGR/FCRL region, which shows a penetrating association in the Asian population, while a complete linkage disequilibrium SNP, rs10917688, is found in a cis-regulatory element for IRF8.

Oct 4, 2023 | nature.com | Ashley Budu-Aggrey |Anna Kilanowski |Maria K Sobczyk |Suyash Shringarpure |Ruth E. Mitchell |Kadri Reis | +68 more

AbstractAtopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery N = 1,086,394, replication N = 3,604,027), combining previously reported cohorts with additional available data.

Oct 2, 2023 | mdpi.com | Masahiro Tsuji |Nao Tanaka |Yoshiaki Sato |Hitomi Koike

1. IntroductionEpidemiological studies have shown that the intrauterine environment is crucial for the future health of each individual, i.e., a concept of DOHaD (developmental origins of health and disease) [1]. Such influence has been particularly shown for cardiovascular diseases, obesity, type 2 diabetes, renal diseases, metabolic syndrome, and sarcopenia [1,2,3].

Sep 8, 2023 | pubs.acs.org | Nao Tanaka |Joshua Zhu |Oniya L. Valencia |Cullen R. Schull

Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2023, XXXX, XXXRETURN TO ARTICLES ASAPPREVCommunicationNEXTNao TanakaDepartment of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States, Joshua L. ZhuDepartment of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States, Oniya L.

Sep 8, 2023 | dx.doi.org | Nao Tanaka |Joshua Zhu |Oniya L. Valencia |Cullen R. Schull

CCDC 2292158 and 2293078 contain the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, or by emailing [email protected], or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, U.K.; fax: +44 1223 336033. Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions.