Natasha W. Hanners

Dec 29, 2023 | mdpi.com | Esra Akkoyun |bilal ashraf |Natasha W. Hanners |Jeffrey Kahn

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.

Jul 13, 2023 | nature.com | Katrina B. Mar |Alexandra Wells |Natasha W. Hanners |Bret M. Evers |John M. Shelton

AbstractLY6E is an antiviral restriction factor that inhibits coronavirus spike-mediated fusion, but the cell types in vivo that require LY6E for protection from respiratory coronavirus infection are unknown. Here we used a panel of seven conditional Ly6e knockout mice to define which Ly6e-expressing cells confer control of airway infection by murine coronavirus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).