-
Aug 11, 2024 | 
link.springer.com | Vita-Salute San Raffaele |Neurorehabilitation Unit
AbstractIn the last years, the hypothesis of a close relationship between sleep disorders (SDs) and Parkinson’s disease (PD) has significantly strengthened. Whether this association is causal has been also highlighted by recent evidence demonstrating a neurobiological link between SDs and PD. Thus, the question is not whether these two chronic conditions are mutually connected, but rather how and when this relationship is expressed.
-
Jul 24, 2024 | 
academic.oup.com | Neurorehabilitation Unit |Vita-Salute San Raffaele |Amsterdam UMC |Vrije Universiteit
Multiple sclerosis is an inflammatory, demyelinating and neurodegenerative disease characterized by the progressive accumulation of CNS damage.1 On the other hand, as individuals age, their brains tend to show alterations, including limited plasticity, intra- and extracellular protein accumulation, reduced grey matter (GM) volume, increased white matter (WM) abnormalities and ischaemic lesions.2 In patients with multiple sclerosis, the interplay between the disease and ageing is complex and...
-
Jul 10, 2024 | 
link.springer.com | Neurorehabilitation Unit |Vita-Salute San Raffaele
This is a preview of subscription content, to check access. Get 10 units per month Download Article/Chapter or Ebook 1 Unit = 1 Article or 1 Chapter Cancel anytime Price excludes VAT (USA) Tax calculation will be finalised during checkout. Instant access to the full article PDF. Rent this article via DeepDyve Data availabilityAll data needed to evaluate the conclusions are present in the paper.
-
Mar 20, 2024 | 
link.springer.com | Vita-Salute San Raffaele |Neurorehabilitation Unit
AbstractFatigue is frequent in people with multiple sclerosis (pwMS) impacting physical and cognitive functions. Lower aerobic capacity and regional thalamic volume may be involved in the pathophysiology of fatigue in pwMS. To identify associations between thalamic nuclei volumes, aerobic capacity and fatigue and to investigate whether the influence of aerobic capacity on fatigue in pwMS is mediated by thalamic integrity.
-
Mar 18, 2024 | 
link.springer.com | Vita-Salute San Raffaele |Neurorehabilitation Unit
AbstractThe widespread use of magnetic resonance imaging (MRI) has led to increased detection of individuals exhibiting asymptomatic brain and spinal cord lesions suggestive of multiple sclerosis (MS), defined as “radiologically isolated syndrome” (RIS). Specific criteria have been proposed and updated over time to identify individuals with RIS.
-
Feb 22, 2024 | 
link.springer.com | Vita-Salute San Raffaele |Neuroradiology Unit |Neurorehabilitation Unit
This is a preview of subscription content, to check access. Price excludes VAT (USA) Tax calculation will be finalised during checkout. Instant access to the full article PDF. Rent this article via DeepDyve Data availabilityAll data needed to evaluate the conclusions are present in the paper. Additional data related to this paper may be requested from the corresponding Author, upon reasonable request by qualified academic investigators.
-
Jan 8, 2024 | 
link.springer.com | Maria Antonietta |Vita-Salute San Raffaele |Neurorehabilitation Unit
AbstractTo assess whether dual-task gait/balance training with action observation training (AOT) and motor imagery (MI) ameliorates cognitive performance and resting-state (RS) brain functional connectivity (FC) in Parkinson’s disease (PD) patients with postural instability and gait disorders (PIGD).
-
Dec 28, 2023 | 
link.springer.com | Neurorehabilitation Unit |Vita-Salute San Raffaele |Neuroradiology Unit
This is a preview of subscription content, to check access. Price excludes VAT (USA) Tax calculation will be finalised during checkout. Instant access to the full article PDF. Rent this article via DeepDyve Data availabilityAnonymized data not published within this article will be made available by request from qualified investigators. ReferencesNakayama M et al (2021) A review of clinical and imaging findings in tumefactive demyelination.
-
Dec 19, 2023 | 
link.springer.com | Neurorehabilitation Unit |Vita-Salute San Raffaele
AbstractMonoaminergic network dysfunction is thought to underpin depression in multiple sclerosis (MS) patients. However, longitudinal studies are lacking. Here, we investigated the association between development of depressive symptoms in MS and changes of resting-state functional connectivity (RS FC) within monoaminergic networks.
-
Nov 28, 2023 | 
link.springer.com | Vita-Salute San Raffaele |Neurorehabilitation Unit
AbstractMost of DYT genotypes follow an autosomal dominant inheritance pattern with reduced penetrance; the mechanisms underlying the disease development remain unclear. The objective of the study was to investigate cortical thickness, grey matter (GM) volumes and white matter (WM) alterations in asymptomatic (DYT-A) and symptomatic dystonia (DYT-S) mutation carriers.
