Olivier Restif

Aug 13, 2024 | medrxiv.org | Liza Hadley |Alex Tasker |Olivier Restif |Caylyn Rich

The authors have declared no competing interest. LH acknowledges support from the Wellcome Trust (block grant no. RG92770). SF also acknowledges support from the Wellcome Trust (grant no. 210758/Z/18/Z). I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Oct 14, 2023 | nature.com | Xiaoliang Ba |Olivier Restif |Benjamin P. Howden |Anders Larsen |Mark Holmes |Lina Maria Cavaco | +1 more

AbstractGlobal spread of multidrug-resistant, hospital-adapted Staphylococcus epidermidis lineages underscores the need for new therapeutic strategies. Here we show that many S. epidermidis isolates belonging to these lineages display cryptic susceptibility to penicillin/β-lactamase inhibitor combinations under in vitro conditions, despite carrying the methicillin resistance gene mecA. Using a mouse thigh model of S.