Ottavia Dipasquale

1 month ago | nature.com | Alessio Giacomel |Daniel Martins |Oliver Howes |Pierluigi Selvaggi |Federico Turkheimer |Ottavia Dipasquale | +1 more

AbstractMolecular neuroimaging techniques, like PET and SPECT, offer invaluable insights into the brain’s in-vivo biology and its dysfunction in neuropsychiatric patients. However, the transition of molecular neuroimaging into diagnostics and precision medicine has been limited to a few clinical applications, hindered by issues like practical feasibility, high costs, and high between-subject heterogeneity of neuroimaging measures.

Jan 18, 2024 | nature.com | Cathy Davies |Daniel Martins |Ottavia Dipasquale |Dominic Oliver |Steve Williams |Philip K. McGuire | +1 more

AbstractAbnormalities in functional brain networks (functional connectome) are increasingly implicated in people at Clinical High Risk for Psychosis (CHR-P). Intranasal oxytocin, a potential novel treatment for the CHR-P state, modulates network topology in healthy individuals. However, its connectomic effects in people at CHR-P remain unknown.