Ouli Xie

Nov 1, 2024 | ausdoc.com.au | Ouli Xie |Asha C Bowen

Need to know: Strep A (Streptococcus pyogenes or group A streptococcus) is estimated to cause over 18 million cases of severe disease and 500,000 deaths worldwide each year.1 × Welcome to AusDoc. Enabling and empowering the medical community to come together. Sign in If this is your first visit to the new AusDoc website, reset your password here.

Apr 24, 2024 | nature.com | Ouli Xie |Cameron Zachreson |David Price |Jake A. Lacey |Jacqueline Morris |Asha C Bowen | +4 more

AbstractStreptococcus dysgalactiae subspecies equisimilis (SDSE) and Streptococcus pyogenes share skin and throat niches with extensive genomic homology and horizontal gene transfer (HGT) possibly underlying shared disease phenotypes. It is unknown if cross-species transmission interaction occurs. Here, we conduct a genomic analysis of a longitudinal household survey in remote Australian First Nations communities for patterns of cross-species transmission interaction and HGT.

Mar 12, 2024 | nature.com | Ouli Xie |Jacqueline Morris |Andrew Hayes |Magnus G. Jespersen |John Lees |Sarah L. Baines | +8 more

AbstractStreptococcus dysgalactiae subsp. equisimilis (SDSE) is an emerging cause of human infection with invasive disease incidence and clinical manifestations comparable to the closely related species, Streptococcus pyogenes. Through systematic genomic analyses of 501 disseminated SDSE strains, we demonstrate extensive overlap between the genomes of SDSE and S. pyogenes.