Paediatric Endocrinology

Feb 6, 2024 | academic.oup.com | Paediatric Haematology |Christian-Albrechts-University Kiel |Paediatric Endocrinology |Justus Liebig

Adrenocortical carcinomas are very rare malignancies in childhood associated with poor outcome in advanced disease. Most adrenocortical tumors (ACT) are functional, causing signs and symptoms of adrenal hormone excess. In most studies, endocrine manifestations were reported 4 to 6 months prior to diagnosis. We sought to extend knowledge on endocrine manifestations with regard to age and sex to facilitate early diagnosis.