
Paul McMillan
Managing Editor at With Intelligence
Heading up the global editorial teams at With Intelligence, providing actional intel to sales and IR pros across asset management.
Articles
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1 month ago |
biorxiv.org | Joydeep Baral |Ching-Seng Ang |Paul McMillan |Kalyan Shobhana
AbstractNon-homologous end joining (NHEJ) is the sole pathway for repairing double-strand breaks (DSBs) in Mycobacterium tuberculosis during dormancy, relying on mycobacterial Ku (mKu) and ligase D, with mKu as the rate-limiting factor. Despite its essential role, the lack of structural information on prokaryotic Ku has hindered understanding of the molecular mechanisms underlying bacterial two-component NHEJ machinery.
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Aug 18, 2023 |
nature.com | Emma Pietsch |Dawson B Ling |Paul McMillan |Paul Gilson |Leann Tilley
AbstractThe malaria parasite uses actin-based mechanisms throughout its lifecycle to control a range of biological processes including intracellular trafficking, gene regulation, parasite motility and invasion. In this work we assign functions to the Plasmodium falciparum formins 1 and 2 (FRM1 and FRM2) proteins in asexual and sexual blood stage development. We show that FRM1 is essential for merozoite invasion and FRM2 is required for efficient cell division.
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Loved the passion on the pitch and touchline today @AFCWimbledon. Our young lads running at them all game and getting hacked apart by their supposed betters. One terrible ref decision away from 3 points. They will come.

Goldman Sachs has been toppled as the top US hedge fund prime broker by AUM for the first time since 2011. Equity-focused rival Morgan Stanley is now the biggest, although GS is still just top in terms of mandates. Data from @HFM_Global https://t.co/daeo5DzTTJ

Gutted not to be at the @afcwimbledon Plough Lane homecoming but what a come back led by lads from the youth. Bolton had no answers for dealing with @ayoubassal17, @anthartigan was class again in the middle and unstoppable header from Will