Phung N. Thai

Jan 16, 2024 | nature.com | Maria C. Perez-Flores |Seojin Park |Yingying Chen |Mincheol Kang |Phung N. Thai |Ryan Woltz | +5 more

AbstractThe inner ear is the hub where hair cells (HCs) transduce sound, gravity, and head acceleration stimuli to the brain. Hearing and balance rely on mechanosensation, the fastest sensory signals transmitted to the brain. The mechanoelectrical transducer (MET) channel is the entryway for the sound-balance-brain interface, but the channel-complex composition is not entirely known. Here, we report that the mouse utilizes Piezo1 (Pz1) and Piezo2 (Pz2) isoforms as MET-complex components.

Jun 5, 2023 | frontiersin.org | Phung N. Thai |Jinan Wang |Eugenia V. Gurevich

Yuanqiang Li1, Boyu Li4, Wei-Dong Chen2,3* and Yan-Dong Wang1* 1State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China 2Key Laboratory of Receptors-Mediated Gene Regulation and Drug Discovery, School of Basic Medical Science, Inner Mongolia Medical University, Hohhot, China 3Key Laboratory of Receptors-Mediated Gene Regulation, School of Medicine, The People’s Hospital of Hebi, Henan University,...