Qiong Yang

Sep 8, 2024 | nature.com | Shahzad Ahmad |Aniket Mishra |Marisol Herrera-Rivero |Joshua C. Bis |Myriam Fornage |Gennady V Roshchupkin | +13 more

AbstractNeurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker of neuro-axonal damage across a range of neurodegenerative disorders. Elucidation of the genetic architecture of blood NfL levels could provide new insights into molecular mechanisms underlying neurodegenerative disorders.

Sep 30, 2023 | mdpi.com | Qiong Yang

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Sep 29, 2023 | ascpt.onlinelibrary.wiley.com | Abdul Wahid |Juan Wen |Qiong Yang |Zhihui Zhang

WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? An observational case–control study was conducted, including 157 patients and 50 healthy controls. Of the patients, 55 had acute myocardial infarction (AMI) without heart failure (HF; AMI−HF), 42 had AMI with HF (AMI+HF), and 60 had HF without AMI (HF−AMI). The high mobility group box 1 (HMGB1) is an active biochemical factor early started to increase in the blood of patients with AMI−HF and can be used as a biomarker of AMI−HF.

Feb 9, 2023 | nature.com | Itziar de Rojas |Najada Stringa |Anna Zettergren |Rebecca Sims |Céline Bellenguez |Miguel Calero | +79 more

Author notesThese authors contributed equally: Itziar de Rojas, Sonia Moreno-Grau, Niccolo Tesi, Benjamin Grenier-Boley, Victor Andrade, Iris E. Jansen. These authors jointly supervised this work: Jordi Clarimón, Mercè Boada, Wiesje M. van der Flier, Alfredo Ramirez, Jean-Charles Lambert, Sven J. van der Lee, Agustín Ruiz.