Queenie Tan

Jan 10, 2025 | cell.com | Ivan K. Chinn |Jonathan May |Anu Goenka |Kate Chandler |Jennifer E. Posey |Alexandra Afenjar | +88 more

Keywords BCL11B C2H2-type zinc finger protein recognition code genotype-phenotype correlation type 2 innate lymphoid cells Introduction Proteins containing a Cys2-His2 zinc-finger domain (C2H2-ZnF) constitute the largest class of human transcription factors.1 They act by either repressing or activating the expression of target genes through binding a specific DNA sequence by their tandem and modular C2H2-ZnFs. Each C2H2-ZnF shares a consensus sequence that folds in the presence of zinc (Zn2+)...

Jan 10, 2025 | cell.com | Ivan K. Chinn |Jonathan May |Anu Goenka |Kate Chandler |Jennifer E. Posey |Alexandra Afenjar | +88 more

Keywords BCL11B C2H2-type zinc finger protein recognition code genotype-phenotype correlation type 2 innate lymphoid cells Introduction Proteins containing a Cys2-His2 zinc-finger domain (C2H2-ZnF) constitute the largest class of human transcription factors.1 They act by either repressing or activating the expression of target genes through binding a specific DNA sequence by their tandem and modular C2H2-ZnFs. Each C2H2-ZnF shares a consensus sequence that folds in the presence of zinc (Zn2+)...

Dec 4, 2024 | pericles.pericles-prod.literatumonline.com | Queenie Tan |Rachel Mahoney |Rebecca C. Spillmann |Allyn McConkie-Rosell

Conflicts of Interest Jill A. Rosenfeld, James P. Orengo, and Daryl A. Scott are employees of Baylor College of Medicine and derive support through a professional services agreement with Baylor Genetics, which performs clinical genetic testing services. All other authors declare no conflict of interest.

Dec 4, 2024 | onlinelibrary.wiley.com | Queenie Tan |Allyn McConkie-Rosell |Rachel Mahoney |Rebecca C. Spillmann

Conflicts of Interest Jill A. Rosenfeld, James P. Orengo, and Daryl A. Scott are employees of Baylor College of Medicine and derive support through a professional services agreement with Baylor Genetics, which performs clinical genetic testing services. All other authors declare no conflict of interest.