Qun Jiang

Dec 30, 2024 | genomebiology.biomedcentral.com | Xiaoyang Chen |Keyi LI |Xiaoqing Wu |Zhen Li |Qun Jiang |Xuejian Cui | +3 more

To capture spatial accessibility pattern of each peak, Descart construct a spatial graph based on spatial locations of spots (can also be replaced by cells).

Apr 15, 2024 | academic.oup.com | Qun Jiang

With the rapid advancement of single-cell sequencing technology, it becomes gradually possible to delve into the cellular responses to various external perturbations at the gene expression level. However, obtaining perturbed samples in certain scenarios may be considerably challenging, and the substantial costs associated with sequencing also curtail the feasibility of large-scale experimentation.