Zhen Li

4 weeks ago | onlinelibrary.wiley.com | Zhimin Gao |Lei Zhang |Zhen Li |Xu Qin

1 Introduction There is an increasing variety of treatment options regarding locally advanced or metastatic urothelial carcinoma (UC), such as immune checkpoint inhibitors (ICIs) [1], antibody–drug conjugates (ADCs) [2], and fibroblast growth factor receptor (FGFR) inhibitors [3]. Nevertheless, the standard initial therapeutic approach for advanced bladder cancer (BC) still involves combination chemotherapy based on cisplatin [4].

2 months ago | nature.com | Yuyao Liu |Zhen Li |Xiaoyang Chen |Xuejian Cui |Zijing Gao

AbstractRecent advances in spatial epigenomic techniques have given rise to spatial assay for transposase-accessible chromatin using sequencing (spATAC-seq) data, enabling the characterization of epigenomic heterogeneity and spatial information simultaneously.

Jan 21, 2025 | opg.optica.org | Miao Yuan |Zhen Li |Weichen Huang |ZhaoXuan Li

Scanning technology is widely used in current lithography. During scanning, any point on the wafer scanning through the field of view (FOV) is successively affected by varying levels of polarization aberrations (PAs) that depend on the position within the FOV. However, current computational lithography studies for extreme ultraviolet lithography (EUVL) neglect this effect of the “dynamic PA” caused by scanning.

Jan 17, 2025 | biorxiv.org | Zhen Li |Xuejian Cui |Xiaoyang Chen |Zijing Gao

AbstractSpatially resolved sequencing technologies have revolutionized our understanding of biological regulatory processes within the microenvironment by accessing the states of genomic regions, genes and proteins as well as spatial coordinates of cells. However, discrepancies between different modalities and samples hinder the analysis of spatial omics data, necessitating the development of advanced computational methods.

Jan 16, 2025 | mdpi.com | Zhen Li |Xueping Liu |Peihao Tang |Xuanlin Wang

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