
Articles
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Jan 21, 2025 |
atlanticcouncil.org | Diane Mohamed |Rachel Friedman |Lynn Monzer |Nibras Basitkey
The Atlantic Council’s Women Innovators (WIn) Fellowship will host its third event for the Jordan cohort on Tuesday, January 28 at 10:00 a.m. ET (6:00 p.m. Amman time). This event, the third of four workshops organized for the WIn Fellowship’s Jordan cohort, will aim to explore how startups are successfully positioning the country as an innovation-driven economy and contributing to the growth of the region’s impact-driven businesses.
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Nov 2, 2024 |
nature.com | Diemmy Nguyen |Laurel Darragh |Mike W. Matsumoto |Benjamin Van Court |Alexander Nguyen |Shilpa Bhatia | +7 more
AbstractThe EphB4-ephrinB2 signaling axis has been heavily implicated in metastasis across numerous cancer types. Our emerging understanding of the dichotomous roles that EphB4 and ephrinB2 play in head and neck squamous cell carcinoma (HNSCC) poses a significant challenge to rational drug design. We find that EphB4 knockdown in cancer cells enhances metastasis in preclinical HNSCC models by augmenting immunosuppressive cells like T regulatory cells (Tregs) within the tumor microenvironment.
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Nov 2, 2024 |
nature.com | Diemmy Nguyen |Laurel Darragh |Mike W. Matsumoto |Benjamin Van Court |Alexander Nguyen |Shilpa Bhatia | +7 more
AbstractThe EphB4-ephrinB2 signaling axis has been heavily implicated in metastasis across numerous cancer types. Our emerging understanding of the dichotomous roles that EphB4 and ephrinB2 play in head and neck squamous cell carcinoma (HNSCC) poses a significant challenge to rational drug design. We find that EphB4 knockdown in cancer cells enhances metastasis in preclinical HNSCC models by augmenting immunosuppressive cells like T regulatory cells (Tregs) within the tumor microenvironment.
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Sep 27, 2024 |
atlanticcouncil.org | Diane Mohamed |Rachel Friedman |Lynn Monzer |Nibras Basitkey
The Atlantic Council’s WIn Fellowship will host a roundtable discussion to tackle recent developments and policy initiatives, key sectors where Saudi women are making strides, the role of digital platforms in empowering female entrepreneurs, and predictions for the future of women entrepreneurship in Saudi Arabia.
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May 10, 2024 |
biorxiv.org | Laura Pyle |Rachel Friedman |Vira Kravets |Nirmala V Balasenthilkumaran
AbstractOne of the challenges in studying islet inflammation - insulitis - is that it is a transient phenomenon. Traditional reporting of the insulitis progression is based on cumulative, donor-averaged values of leucocyte density in the vicinity of pancreatic islets, that hinders intra- and inter-islet heterogeneity of disease progression. Here, we aimed to understand why insulitis is non-uniform, often with peri-insulitis lesions formed on one side of an islet.
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