Rebecca Hoh

Nov 28, 2024 | cell.com | Milica Moskovljevic |Filippo Dragoni |Nathan L. Board |Fengting Wu |Jun S. Lai |Hao Zhang | +10 more

Keywords HIV-1 persistence HIV-1 latent reservoir latency reversal antigenic stimulation dendritic cells CD4+ T cells cytomegalovirus Introduction Antiretroviral therapy (ART) effectively blocks viral replication, but HIV-1 persists in a small pool of latently infected resting CD4+ T cells harboring inducible, replication-competent proviruses.1,2,3 This reservoir was originally characterized with a quantitative viral outgrowth assay (QVOA) in which resting CD4+ T cells are stimulated with...

Mar 28, 2024 | medrxiv.org | Rebecca Hoh |Alton Barbehenn |Junzhe Shao |Heather M Hartig

The authors have declared no competing interest. NCT02656511The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.