Richard Goodman

2 months ago | mdpi.com | Muhammad Humayun |Saadia Naseem |Richard Goodman |Zahid Ali

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Oct 17, 2024 | nature.com | Fabrice E Graf |Richard Goodman |Esther Picton-Barlow |Minh-Duy Phan |Mark Schembri |Adam Roberts | +2 more

AbstractInfections with Enterobacterales (E) are increasingly difficult to treat due to antimicrobial resistance. After ceftriaxone replaced chloramphenicol (CHL) as empiric therapy for suspected sepsis in Malawi in 2004, extended-spectrum beta-lactamase (ESBL)-E rapidly emerged. Concurrently, resistance to CHL in Escherichia coli and Klebsiella spp. decreased, raising the possibility of CHL re-introduction.