Robert Sigström

Nov 12, 2024 | lakartidningen.se | Robert Sigström

Egenreferat. Elektrokonvulsiv terapi (ECT) är effektiv vid svår och svårbehandlad depression och en del andra psykiatriska tillstånd. I Sverige är ECT rutinsjukvård sedan decennier och ges årligen till ca 4 000 patienter. I många andra västländer används ECT betydligt mindre. En orsak är minnesbiverkningar och rädsla att dessa skulle bero på att ECT orsakar hjärnskada.

Oct 2, 2024 | nature.com | Robert Sigström |Andreas Göteson |Axel Nordenskjöld |Kaj Blennow |Henrik Zetterberg

AbstractDespite electroconvulsive therapy (ECT) being recognized as an effective treatment for major depressive episodes (MDE), its application is subject to controversy due to concerns over cognitive side effects. The pathophysiology of these side effects is not well understood. Here, we examined the effects of ECT on blood-based biomarkers of neuronal injury and astrocytic reactivity. Participants with a major depressive episode (N = 99) underwent acute ECT.

Mar 27, 2024 | jamanetwork.com | Robert Sigström |Sahlgrenska Academy

Mortality Among Individuals With Hypochondriasis To the Editor I read with interest the article1 by Mataix-Cols and colleagues, who found that individuals who received a diagnosis of hypochondriasis in any type of specialized care in Sweden had a higher mortality risk than age- and sex-matched controls in the general population. This topic is important. The authors present a thorough analysis of the data. I would like to discuss the limitations of these data.