Ryan Wick

Oct 10, 2024 | elifesciences.org | Michael Hall |Ryan Wick |Louise M Judd |An Nguyen |an nguyễn

eLife assessment This important study shows how a combination of the latest generation of Oxford Nanopore Technology long reads with state-of-the art variant callers enables bacterial variant discovery at an accuracy that matches or exceeds the current "gold standard" with short reads. The work thus heralds a new era, in which Illumina short-read sequencing no longer rules supreme.

May 8, 2024 | rrwick.github.io | Ryan Wick

Sometimes during ONT sequencing, after one strand of DNA finishes its trip through a pore, the other strand immediately follows, and there are two different ways that the basecaller can handle this. It can make a separate read from each strand’s signal, what ONT calls simplex sequencing. Or it can basecall both signals together to make a single read with higher accuracy, what ONT calls duplex sequencing.

Apr 17, 2024 | microbiologyresearch.org | Jack Pilgrim |Ryan Wick |Louise M Judd |Kelly L. Wyres

Article metrics loading... /content/journal/mgen/10.1099/mgen.0.001242Download as PowerPoint /deliver/fulltext/mgen/10/4/mgen001242.html?itemId=/content/journal/mgen/10.1099/mgen.0.001242&mimeType=html&fmt=ahah References Ferrari J, Vavre F. Bacterial symbionts in insects or the story of communities affecting communities. Philos Trans R Soc Lond B Biol Sci 2011; 366:1389–1400 [View Article] [PubMed][Google Scholar] Engelstädter J, Hurst GDD.

Feb 9, 2023 | microbiologyresearch.org | Ryan Wick |Louise M Judd |Kelly L. Wyres |Claire Gorrie

1 - 3 of3for"Margaret M. C. Lam" PublicationKeywordKlebsiella pneumoniae(3) AMR(1) ICEKp(1) K locus(1) Klebsiella capsule K-locus genomic surveillance(1) MLST(1) Nanopore sequencing(1) O locus(1) bacterial pathogens(1) basecalling(1) benchmarking(1) colibactin(1) genomic surveillance(1) mobile genetic elements(1) phylogenetic clustering(1) serotyping(1) virulence(1) yersiniabactin(1) Show moreShow lessContent typeAccess Type