Samuel Kim

Nov 21, 2024 | genome.cshlp.org | Samuel Kim |Georgi K. Marinov |William J. Greenleaf |Chan Zuckerberg Biohub

2 1 Stanford University; 2 Stanford University, Chan Zuckerberg Biohub ↵* Corresponding author; email: marinovg{at}stanford.edu Received May 24, 2024. Accepted November 19, 2024. This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see https://genome.cshlp.org/site/misc/terms.xhtml).

Aug 14, 2024 | jbc.org | Samuel Kim |New Brunswick

AbstractThe tricarboxylic acid (TCA) cycle plays a crucial role in mitochondrial ATP production in the healthy heart. However, in heart failure, the TCA cycle becomes dysregulated. Understanding the mechanism by which TCA cycle genes are transcribed in the healthy heart is an important prerequisite to understanding how these genes become dysregulated in the failing heart. PGC-1α is a transcriptional coactivator that broadly induces genes involved in mitochondrial ATP production.

May 7, 2024 | biorxiv.org | Samuel Kim |Georgi K. Marinov |William J. Greenleaf

AbstractGene regulation in most eukaryotes involves two fundamental physical processes -- alterations in the packaging of the genome by nucleosomes, with active cis-regulatory elements (CREs) generally characterized by an open-chromatin configuration, and the activation of transcription.

Oct 3, 2023 | newsdirectory3.com | Samuel Kim

Stock Prices Surge as Yuhan Corporation’s New Drug, Lazertinib, Demonstrates Promising Results in Clinical TrialsBy Samuel Kim, Money Today Reporter | 2023.10.04, 09:23 AMStock in QuestionStock prices are experiencing a significant surge following the announcement that Yuhan Corporation’s latest drug, Lazertinib, has shown successful clinical results when combined with Janssen’s bispecific antibody drug, Librevant (ingredient name: amivantamab).