Sandeep Burma

Sep 11, 2024 | nature.com | Sameer Salunkhe |James Daley |Chaoyou Xue |Angela M. Jasper |Wenjing Li |Rahul Mojidra | +8 more

AbstractThe licensing step of DNA double-strand break repair by homologous recombination entails resection of DNA ends to generate a single-stranded DNA template for assembly of the repair machinery consisting of the RAD51 recombinase and ancillary factors1. DNA end resection is mechanistically intricate and reliant on the tumour suppressor complex BRCA1–BARD1 (ref. 2).

Oct 30, 2023 | asbmb.org | Sandeep Burma

I am a recent transplant to San Antonio, having moved here from Dallas where I was a professor of radiation oncology at the University of Texas Southwestern Medical Center. In 2019, I was recruited by the University of Texas Health Science Center at San Antonio where I am a professor of neurosurgery and biochemistry and molecular biology and vice chair (research) of neurosurgery.

Jun 21, 2023 | nature.com | YoungHo Kwon |Maria Jasin |Alexander Taylor |Sandeep Burma |Weixing Zhao |Eric Greene | +1 more

Sung, P. & Klein, H. Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nat. Rev. Mol. Cell Biol. 7, 739–750 (2006). Article  CAS  PubMed  Google Scholar  Sullivan, M. R. & Bernstein, K. A. RAD-ical new insights into RAD51 regulation. Genes https://doi.org/10.3390/genes9120629 (2018). Meindl, A. et al. Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat. Genet. 42, 410–414 (2010).