Sandra Ackermann

Feb 17, 2023 | nature.com | Jana Fassunke |Sandra Ackermann |Martin Peifer |Reinhard Büttner |Johannes H. Schulte |Thorsten Simon | +1 more

AbstractBackgroundGenomic alterations of the anaplastic lymphoma kinase gene (ALK) occur recurrently in neuroblastoma, a pediatric malignancy of the sympathetic nervous system. However, information on their development over time has remained sparse. MethodsALK alterations were assessed in neuroblastomas at diagnosis and/or relapse from a total of 943 patients, covering all stages of disease.