Sangyun Lee

2 months ago | nature.com | Elizabeth Kim |Sangyun Lee |Alessio Accardi

AbstractBK channels are large-conductance calcium (Ca2+)-activated potassium channels crucial for neuronal excitability, muscle contraction, and neurotransmitter release. The pore-forming (α) subunits co-assemble with auxiliary (β and γ) subunits that modulate their function. Previous studies demonstrated that the N-termini of β2-subunits can inactivate BK channels, but with no structural correlate.

Sep 25, 2024 | truthonthemarket.com | Sangyun Lee |Daniel Gilman |Ben Sperry |Mario Zúñiga

The Korea Fair Trade Commission (KFTC), the nation’s competition authority, announced Sept. 9 that it had abandoned plans for comprehensive platform regulation modeled after the European Union’s Digital Markets Act (DMA) or Section 19a of Germany’s Competition Act. The proposed Korean regulation would have involved an ex-ante designation process, alongside stringent prohibitions.

Jul 31, 2024 | nature.com | Elizabeth Kim |Xiaoan Wu |Sangyun Lee |Kevin Cunningham |Marta Perez |Peter Goldstein | +4 more

AbstractHyperpolarization-activated cyclic nucleotide-gated (HCN) channels1 are essential for pacemaking activity and neural signalling2,3. Drugs inhibiting HCN1 are promising candidates for management of neuropathic pain4 and epileptic seizures5. The general anaesthetic propofol (2,6-di-iso-propylphenol) is a known HCN1 allosteric inhibitor6 with unknown structural basis.

Jul 22, 2024 | promarket.org | Sangyun Lee

Sangyun Lee reviews the 2021 merger between Korean Air and Asiana Airlines, which was promoted by the government despite warnings from the majority of experts deeming it obviously anticompetitive and harmful to consumers. He finds that the merger is a paragon of how, under institutional constraints, the rational choices of actors and organizations can collectively lead to irrational, suboptimal outcomes.

Apr 10, 2024 | link.aps.org | Sangyun Lee |Los Alamos |Andrew Woods |Minseong Lee

Article Text (Subscription Required) Click to ExpandReferences (Subscription Required) Click to ExpandIssueVol. 109, Iss. 15 — 15 April 2024Access OptionsBuy Article »Log in with individual APS Journal Account »Log in with a username/password provided by your institution »Get access through a U.S. public or high school library »Article part of CHORUSAccepted manuscript will be available starting10 April 2025. Download & Share××