Satoshi KUBO

Jan 6, 2025 | nature.com | Martin Pehrsson |Anne-Christine Bay-Jensen |Morten Asser Karsdal |Bent Deleuran |Tue W. Kragstrup |Satoshi KUBO | +2 more

AbstractUnderstanding how inflammatory cytokines influence profibrogenic wound healing responses in fibroblasts is important for understanding the pathogenesis of fibrosis. TNF-α and IL-13 are key cytokines in Th1 and Th2 immune responses, respectively, while TGF-β1 is the principal pro-fibrotic mediator.

Oct 4, 2024 | ard.bmj.com | Satoshi KUBO |Yusuke Miyazaki |Takahiro Nishino |Yuya Fujita

Peripheral blood immunophenotypic diversity in patients with rheumatoid arthritis and its impact on therapeutic responsiveness Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Sep 1, 2024 | nature.com | Satoshi KUBO |Yoshiya Tanaka

Immune health has been considered impossible to assess through the use of traditional biomarkers. The newly devised immune health metric (IHM) integrates diverse biological data to quantify immune function, offering a comprehensive indicator for the evaluation of immune health. The potential of the IHM to distinguish healthy individuals from patients with monogenic or polygenic immune-mediated diseases might lead to revolutionary changes in treatment strategies for rheumatic diseases.

Jul 25, 2024 | emjreviews.com | Satoshi KUBO |Yoshiya Tanaka

INTRODUCTIONAn ageing society is characterised by the elderly population, classified as individuals aged 65 years or older, constituting ≥7% of the total population. Furthermore, when the ageing rate reaches 14%, the designation shifts to an aged society, and upon reaching 21%, it is termed a super-aged society.

Feb 12, 2024 | nature.com | Ann Park |Justin Q. Gabrielski |Hyoungjun Ham |Jean Michel Chanchu |Aaron R. Morawski |Aiman J. Faruqi | +14 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01691-y, published online 3 January 2024. In the version of the article initially published, Buket Dalgıç (Department of Pediatric Gastroenterology, Gazi University Faculty of Medicine, Ankara, Turkey) was mistakenly omitted from the author list and has now been added in the HTML and PDF versions of the article. About this articlePark, A.Y., Leney-Greene, M., Lynberg, M. et al.