Sean Hui

2 months ago | cell.com | Saravanan Raju |Sathvik Palakurty |Alan Sariol |Ngan Wagoner |Lucas Adams |Sean Hui | +3 more

Keywords alphavirus receptor structure pathogenesis therapy cryoelectron microscopy Introduction Alphaviruses are arthropod-transmitted viruses that infect many vertebrate hosts.1 The encephalitic alphaviruses, including Eastern equine encephalitic virus (EEEV), Venezuelan equine encephalitic virus (VEEV), and Western equine encephalitic virus (WEEV), are neurotropic in both horses and humans and cause lethality or long-term neurological sequelae.2 Whereas some bird species serve as enzootic...