Sebastian Dohm-Hansen

Jul 19, 2024 | biorxiv.org | Sebastian Dohm-Hansen |Sarah Nicolas |Erin Harris |Minke HC Nota

AbstractAnimal studies have shown that a cafeteria (CAF) diet (high in saturated fat and sugar), is associated with memory impairments and increased anxiety, while exercise can enhance antidepressant-like effects and cognitive function.

Apr 23, 2024 | nature.com | Sarah Nicolas |Sebastian Dohm-Hansen |John Cryan

AbstractLifestyle factors, especially exercise, impact the manifestation and progression of psychiatric and neurodegenerative disorders such as depression and Alzheimer’s disease, mediated by changes in hippocampal neuroplasticity. The beneficial effects of exercise may be due to its promotion of adult hippocampal neurogenesis (AHN).

Mar 19, 2024 | cell.com | Sebastian Dohm-Hansen |APC Microbiome Ireland |Jane English |Aonghus Lavelle

HighlightsMiddle age (roughly the fifth and sixth decades of human life) has historically been understudied compared to more advanced age, but is emerging as marking a possible shift in brain aging that is predictive of future cognitive health, while still being amenable to intervention. Some age-related changes of the brain display approximately linear trajectories throughout adult life, whereas others change non-linearly in a life stage-specific manner.