Seth Scanlon

Sep 26, 2024 | science.org | Qiuhe Lu |J. G. Muir |Seth Scanlon |Z. Chahine

Immunometabolism Fever drives mitochondrial damageSeth T. ScanlonFever can enhance the function of T cells, seen here here in a colored scanning electron microscopy image with a cancer cell. PHOTO: STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARYHeat is one of the hallmarks of inflammation, but its effect on immune cells is not well understood. Heintzman et al.

Jan 4, 2024 | science.org | Erkan Aydin |Phil Szuromi |Seth Scanlon |Jake Yeston

Perovskites A supramolecular boost to emissionPhil SzuromiPhotoluminescent inorganic compounds embedded in a polymer can be used to create dual-color three-dimensional structures. Open in viewerMany inorganic perovskites can show strong photoluminescence, including ones based on hafnium and zirconium halides, but these compounds are often air and water sensitive. Zhu et al.

Sep 14, 2023 | science.org | Robin J. Dart |Eric J. Topol |Sriram Balusu |Seth Scanlon

Research HighlightsNeuroimmunology Peptide promotes protectionSeth Thomas ScanlonNeuromedin U (NMU) is a neuropeptide that can drive the type 2 immune responses seen in allergy and antihelminth host defense by activating group 2 innate lymphoid cells that express the receptor NMUR1. Whether NMU activates other players in type 2 immunity remains controversial. Using single-cell RNA sequencing and fate-mapping reporter mice, Li et al.

Sep 7, 2023 | science.org | Xiangdong Lv |Moritz Peiseler |Guojun He |Seth Scanlon

Research HighlightsImmunometabolism Does chitin help metabolic health? Seth Thomas ScanlonOpen in viewerChitin (β-1,4-poly-N-acetylglucosamine) is a highly abundant natural polysaccharide found in arthropods and fungi that can initiate type 2 (allergic) immune responses. Kim et al. report in mice that the consumption of chitin triggers gastric distension, downstream neuropeptide release, and type 2 cytokine production by tuft cells and type 2 innate lymphoid cells.

Jun 29, 2023 | science.org | Seth Scanlon