Seunggeun Lee

Nov 7, 2024 | medrxiv.org | Jack Flanagan |Kisung Nam |Seunggeun Lee

The authors have declared no competing interest. This research was supported by the Brain Pool Plus (BP+) Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (2020H1D3A2A03100666). This research was conducted using the UKBB Resource under application number 45227. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Oct 24, 2024 | medrxiv.org | Na Yeon Kim |Seunggeun Lee

The authors have declared no competing interest. This study was supported by Brain Pool Plus (Brain Pool+) Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT [2020H1D3A2A03100666]. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Sep 18, 2023 | nature.com | Adrian Campos |Shinichi Namba |Julia Sidorenko |Huanwei Wang |Seunggeun Lee |Yen-Feng Lin | +3 more

AbstractGenome-wide association studies (GWASs) have been mostly conducted in populations of European ancestry, which currently limits the transferability of their findings to other populations. Here, we show, through theory, simulations and applications to real data, that adjustment of GWAS analyses for polygenic scores (PGSs) increases the statistical power for discovery across all ancestries.