Seyedmohammad Saadatagah

Oct 28, 2024 | digitalcommons.library.tmc.edu | Seyedmohammad Saadatagah |Mesbah Uddin |Lachelle D. Weeks |Abhishek Niroula

IMPORTANCE: Clonal hematopoiesis (CH) with acquired pathogenic variants in myeloid leukemia driver genes is common in older adults but of unknown prognostic value. OBJECTIVE: To investigate the prevalence of CH and the utility of the CH risk score (CHRS) in estimating all-cause and disease-specific mortality in older adults with CH.

Jan 17, 2024 | jamanetwork.com | Seyedmohammad Saadatagah |Mesbah Uddin |Lachelle D. Weeks

Key PointsQuestion  Is the clonal hematopoiesis (CH) risk score associated with all-cause and disease-specific mortality in older adults with CH? Findings  In this cohort study that included 3871 individuals without hematologic malignant neoplasms at baseline, 24.2% had CH.