Shang Li

Dec 4, 2024 | biorxiv.org | Xuetao Zhang |Kyle Jacobs |Kunal Raygor |Shang Li

AbstractHereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant vascular disorder with manifestations including severe nose bleeding and microhemorrhage in brains. Despite being the second most common inherited bleeding disorder, the pathophysiological mechanism underlying HHT-associated hemorrhage is poorly understood. HHT pathogenesis is thought to follow a Knudsonian two-hit model, requiring a second somatic mutation for lesion formation.

Nov 28, 2024 | biorxiv.org | Xuetao Zhang |Kyle Jacobs |Kunal Raygor |Shang Li

AbstractHereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant vascular disorder with presentations including severe nose bleeding and microhemorrhage in brains. Despite being the second most common inherited bleeding disorder, the pathophysiological mechanism underlying HHT-associated hemorrhage is poorly understood. Mutations in activin receptor-like kinase 1 (ALK1) gene cause HHT type 2.

Aug 1, 2024 | mdpi.com | Yihan Zhang |Xing LI |Shang Li |Yu Zhou

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Mar 20, 2023 | mdpi.com | Chang Liu |Shang Li

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticlebyChang Liu 1,* and Shang Li 1,2 1State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China 2Foshan Xianhu Laboratory of the Advanced Energy Science and Technology Guangdong Laboratory, Foshan 528200, China*Author to whom correspondence should be addressed.