Shizhong Han

Aug 14, 2024 | arxiv.org | Yinghan Chen |Shizhong Han |Ying Lin

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Jul 6, 2023 | frontiersin.org | Neurorehabilitation Unit |Shizhong Han |Shuo Zhang

IntroductionCopy number variation (CNV) is defined as the genomic presence of a given DNA sequence element >50 bp in copy number different from a reference genome. CNVs are a common type of structural variation in eukaryotic genomes, and single nucleotide polymorphism (SNP) microarray technology enables high-throughput, genome-wide detection of CNVs in many species, including humans.

May 15, 2023 | nature.com | Gianluca Ursini |Shizhong Han |Carmen J. Marsit |Ke Hao |Giovanna Punzi

AbstractOur earlier work has shown that genomic risk for schizophrenia converges with early life complications in affecting risk for the disorder and sex-biased neurodevelopmental trajectories. Here, we identify specific genes and potential mechanisms that, in placenta, may mediate such outcomes.