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1 month ago | 
biorxiv.org | Simon Fraser |Shaianne Stein |Lorena Braid
AbstractBasement membrane, the specialized extracellular matrix (ECM) that compartmentalizes endothelial and epithelial cells, is the final frontier in bioengineering. The fibrillar collagens (Col I and Col III) of the interstitial matrix are commonly used for tissue modeling, but the networking collagens that scaffold the basement membrane (human Col IV and Col VI) remain elusive.
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2 months ago | 
bmj.com | Jocalyn Clark |Timothy C. Evans |Timothy Evans |Kelley Lee |Simon Fraser
Jocalyn Clark, international editor1, Timothy Evans, vice president, research, innovation, and impact2, Kelley Lee, professor, global health governance31The BMJ, London, UK2Concordia University, Montreal, Canada3Simon Fraser University, Vancouver, CanadaGreater cooperation in global health is needed to tackle challenges and to harness new opportunities.
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Mar 8, 2025 | 
academic.oup.com | Toronto Metropolitan |Simon Fraser
Social integration – the degree to which a person is socially connected and engaged with other people – is a programmatic goal of supportive housing models and a predictor of successful housing outcomes among clients. While research has examined social integration within permanent supportive housing models, minimal research has considered how social integration may be promoted within temporary housing programs (THPs), particularly for older persons.
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Feb 21, 2025 | 
bmcpublichealth.biomedcentral.com | Simon Fraser
Our results indicate that during the first pandemic wave and the ensuing months, the death rate of people who were free of COVID-19 in BC (i.e., always tested negative) more than tripled that of a matched pre-pandemic cohort.
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Feb 20, 2025 | 
bmj.com | Simon Fraser |Nisreen A Alwan
What next? We clearly need a better language or framework for the prevention of multiple long term conditions to know where our priorities should lie, particularly in the context of limited resources and overwhelmed health systems.10As Geoffrey Rose recognised in his 1981 article on strategies of prevention there is a paradox in taking just a “high risk” approach to health care.
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Jan 27, 2025 | 
genomemedicine.biomedcentral.com | Tropical Diseases |Simon Fraser
We compared the accuracy of our new tool, MixInfect2, against previous methods (MixInfect [6], SplitStrains [16], and QuantTB [18]) for detecting mixed infections and to estimate the major strain proportion from the dataset of 36 in vitro mixed samples and 12 non-mixed (“pure”) strains. The average coverage in all these samples was relatively high, ranging from 356- to 482-fold.
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Dec 4, 2024 | 
journals.plos.org | Jennie Pearson |Andrea Krüsi |Simon Fraser |Kate Shannon
Citation: Pearson J, Krüsi A, Shannon K, Ettinger E, Kerrigan D, Braschel M, et al. (2024) The protective association of social cohesion on sex workers’ experiences of violence and access to community support: Impacts of resource sharing, trust and connection among a community-based cohort in Metro Vancouver, Canada (2010–2022). PLoS ONE 19(12): e0314749.
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Dec 4, 2024 | 
journals.plos.org | Simon Fraser |Caroline Colijn |Arne Mooers |Niloufar Abhari
Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Abhari N, Colijn C, Mooers A, Tupper P (2024) Measuring genetic diversity across populations. PLoS Comput Biol 20(12): e1012651. https://doi.org/10.1371/journal.pcbi.1012651Editor: Philipp Martin Altrock, Max Planck Institute for Evolutionary Biology, GERMANYReceived: May 7, 2024; Accepted: November 18, 2024; Published: December 4, 2024Copyright: © 2024 Abhari et al.
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Nov 26, 2024 | 
bmcmedinformdecismak.biomedcentral.com | Anh N. Q |Claire E. H |Simon Fraser |C. Allyson
The CPCSSN is a pan-Canadian collaboration of practice-based research and surveillance networks that collects, formats, and merges patient-level primary care EMR data [5]. As of December 31, 2020, CPCSSN contained data from two million de-identified primary care patients (including over 1.3 million adults aged 19+) and more than 1,300 primary care physicians’ practices across eight provinces.
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Nov 25, 2024 | 
bmcbioinformatics.biomedcentral.com | Simon Fraser |Lethbridge Research
In this section, we use PlasEval to evaluate four plasmid binning tools on a set of 53 samples from a collection of Escherichia coli genomes sequenced using both short and long reads by Sanderson et al [26]. The isolates in this analysis belong to a collection of E. coli strains collected from Saskatchewan broiler farms by Sanderson et al [26].
